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ea0037oc2.4 | Reproduction | ECE2015

Low free testosterone is associated with hypogonadal symptoms in men with normal total testosterone levels: results from the European Male Ageing Study

Antonio Leen , Wu Frederic , O'Neill Terrence , Pye Stephen , Carter Emma , Finn Joseph , Laurent Michael , Huhtaniemi Ilpo , Rutter Martin , Rastrelli Giulia , Forti Gianni , Bartfai Gyorgy , Casanueva Felipe , Kula Krzysztof , Punab Margus , Giwercman Aleksander , Claessens Frank , Decallonne Brigitte , Vanderschueren Dirk

Background: During ageing, total testosterone (TT) declines and SHBG increases, resulting in a greater decline of free testosterone (FT) compared to TT. However, guidelines suggest using TT to diagnose androgen deficiency and to reserve FT only for men with borderline TT. We investigated if isolated low FT or isolated low TT was associated with androgen-related endpoints in healthy men.Methods: 3369 community-dwelling men, aged 40–79, were included....
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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